Arrhythmias & electrophysiologyResearch article
Lesion Durability of the Second Generation Pentaspline Pulsed Field Ablation Catheter NAVIGATE-PF Phase 2 Results
- first-in-human study
- invasive remapping
Authors' conclusion
By facilitating real-time visualization of catheter positioning and acute lesion estimation through tags, the second-generation map-and-ablate pentaspline PFA catheter and integrated mapping system may enhance procedural success.
Study context
- Population
- Patients with atrial fibrillation undergoing ablation with the second-generation, mapping-integrated pentaspline pulsed field ablation (PFA) catheterindex ablation, remaps performed in 17 patients
- Participants
- 20 patients
Main finding
As reported in the abstract
Lesion durability by invasive remapping · 60 days post index procedure
pulmonary veins
95%
posterior wall
86%
Original publication
Lesion Durability of the Second Generation Pentaspline Pulsed Field Ablation Catheter NAVIGATE-PF Phase 2 Results. Circ Arrhythm Electrophysiol. Published 1 April 2026. doi:10.1161/circep.125.014477
Summarised from the published abstract; every number is checked against it