Valvular & structural heart disease

Linear Ablation at the Mitral Isthmus Following Mitral Valve Surgery

JACC Clin ElectrophysiolPublished Retrospective study with propensity score-matched control group

Authors' conclusion

EIVOM and mitral isthmus ablation are feasible and acutely successful after mitral valve surgery.

Study context

Population
Patients with prior mitral valve surgery undergoing EIVOM and mitral isthmus ablation
Exposure
Mitral valve-operated patients vs propensity score-matched control group
  • Control groupn = 72
Outcome
EIVOM success
Methodological detailsconsecutive patients, propensity-weighted analysis
  • Consecutive patients
  • Propensity-weighted analysis

Main finding

As reported in the abstract

EIVOM successful (study group)

92.6%

Observational data: associations, not effects.

Further findings

EIVOM success rate (propensity-weighted)

Acutely unblocked mitral isthmus

Freedom from atrial tachycardia/atrial fibrillation · 1 year

  • EIVOM success rate (propensity-weighted): P = 0.76
  • Acutely unblocked mitral isthmus: P = 0.073
  • Freedom from atrial tachycardia/atrial fibrillation: P = 0.12

Acute mitral isthmus block

Acute mitral isthmus block achieved (study group)
88.9%

Baseline characteristics (study group)

Mean age
64 ± 12 years
Mean left atrial volume index
56 ± 18 mL/m²
Male
53.7%
Mitral valve replacement
74.1%
Mechanical valves, of those with mitral valve replacement
52.5%

Safety

VOM dissection

  • VOM dissection: P = 0.30

Original publication

Linear Ablation at the Mitral Isthmus Following Mitral Valve Surgery. JACC Clin Electrophysiol. Published 3 July 2025. doi:10.1016/j.jacep.2025.05.009

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