Coronary disease & ACSCohort study
Lipoprotein(a) and long-term in-stent restenosis after percutaneous coronary intervention
- Retrospective cohort study
- 3 Mayo Clinic sites
Authors' conclusion
Lipoprotein(a) is an independent predictor for long-term ISR
Study context
- Population
- Adults after successful percutaneous coronary intervention (PCI) with preprocedural Lp(a) measurement, 2006–2017
- Participants
- 1,209 adults
- Exposure
- High Lp vs low Lp
- Outcome
- In-stent restenosis (ISR)
- Follow-up
- Median 8.8 years
Main finding
ISR
Hazard ratio
1.67
95% CI 1.18–2.37
P = 0.004
By group
High Lp(a) vs Low Lp(a)
HR 1.67 (95% CI 1.18–2.37); P = 0.004
As reported in the abstract
Observational data: associations, not effects.
Further findings
Serum Lp(a), ISR vs no ISR
P = 0.008
Overall in-stent restenosis (ISR)
- Restenosis observed
- 162 (13.4%)
Original publication
Lipoprotein(a) and long-term in-stent restenosis after percutaneous coronary intervention. Eur J Prev Cardiol. Published 24 June 2024. doi:10.1093/eurjpc/zwae212
Summarised from the published abstract; every number is checked against it