Valvular & structural heart diseaseSecondary analysis
Long-Term Clinical and Echocardiographic Outcomes Following the Ross Procedure
- Post hoc analysis of a randomised clinical trial
- single-centre
- retrospective data collection after 2010
Trial conducted September 1, 1994, to May 31, 2001; median clinical follow-up 24.1 years (IQR, 22.6-26.1 years; 2488 patient-years)
Authors' conclusion
This study found that the Ross procedure provided excellent survival into the third decade postoperatively that was comparable to that in the general population.
Study context
- Population
- Adults (age <69 years) with aortic valve disease undergoing the Ross procedure, incl. active endocarditis, rheumatic AVD, decreased EF and previous cardiac surgery98% follow-up completeness
- Participants
- 108 adults
- Comparison
- Ross procedure vs General population
- Ross proceduren = 108
- Primary endpoint
- Long-term survival vs matched general population
- Follow-up
- 25 years
Primary result
Survival
Relative survival
99.1%
95% CI 91.8%–100%
By group
As reported in the abstract
Secondary outcomes
Freedom from reintervention · 25 years
- Freedom from any reintervention
- 71.1% (95% CI, 61.6%-82.0%)
- Freedom from autograft reintervention
- 80.3% (95% CI, 71.9%-89.6%)
- Freedom from homograft reintervention
- 86.3% (95% CI, 79.0%-94.3%)
Outcomes after Ross-related reintervention
- 30-day mortality after first Ross-related reintervention
- 0%
- 30-day mortality after all Ross-related reinterventions
- 3.8% (n = 1)
- 10-year survival after reoperation
- 96.2% (95% CI, 89.0%-100%)
Original publication
Long-Term Clinical and Echocardiographic Outcomes Following the Ross Procedure. JAMA Cardiol. Published 1 January 2024. doi:10.1001/jamacardio.2023.4090
Summarised from the published abstract; every number is checked against it