Heart failure & cardiomyopathiesSecondary analysis
Long-Term Clinical Outcomes and Healthcare Resource Utilization in Male and Female Patients Following Hospitalization for Heart Failure
- Secondary analysis of the PACT-HF randomised trial
- exploratory analysis
- cluster-randomised
- 10 Canadian hospitals
- Outcomes obtained via linkages with administrative datasets
Authors' conclusion
Among people discharged alive after hospitalization for HF, there were no sex differences in total and annual deaths, readmissions, and ED visits, or in total direct healthcare costs.
Study context
- Population
- Patients discharged alive after hospitalization for heart failure (HF) across 10 Canadian hospitals50.7% female
- Participants
- 4,441 patients
- Comparison
- Male vs female patients
- Primary endpoint
- All-cause mortality
- Follow-up
- 5 years
Primary result
As reported in the abstract
P = 0.19
Secondary outcomes
| Outcome | Values | P value |
|---|---|---|
| Readmitted · 5 years | Male 85.4% · Female 84.4% | P = 0.35 |
| ED care without hospitalization · 5 years | Male 72.2% · Female 70.9% | P = 0.34 |
| All-cause readmissions per person | Male mean 2.8 (SD 7.8) · Female mean 3.0 (SD 8.4) | P = 0.54 |
| HF readmissions per person | Male mean 0.9 (SD 3.6) · Female mean 0.9 (SD 4.5) | P = 0.80 |
| ED visits per person | Male mean 1.8 (SD 11.3) · Female mean 1.5 (SD 6.0) | P = 0.24 |
| Annual direct healthcare cost per patient | Male mean 80 334 (SD 116 762) $ · Female mean 81 010 (SD 112 625) $ | P = 0.90 |
Healthcare resource use by type
- Males received more specialist, multidisciplinary HF clinic, haemodialysis and day surgical care
- Females received more home visits, continuing/convalescent care and long-term care
- Annualized clinical events highest in first year after index discharge in both sexes
Original publication
Long-Term Clinical Outcomes and Healthcare Resource Utilization in Male and Female Patients Following Hospitalization for Heart Failure. Eur J Heart Fail. Published 5 November 2024. doi:10.1002/ejhf.3499
Summarised from the published abstract; every number is checked against it