Congenital heart diseaseCohort study
Long-Term Electrophysiologic Comorbidities After Anatomically Repaired Congenitally Corrected Transposition of the Great Arteries
- retrospective cohort study
- single center
Authors' conclusion
Patients who underwent AR are at significant risk for developing AT, even within a short timeframe after the index surgery, with increasing incidence over time. The need for atrioventricular valve reintervention after AR increases the risk of AT.
Study context
- Population
- Patients who underwent anatomic repair for ccTGA between 1993 and 2017cohort
- Participants
- 85 patients
- Exposure
- Need for atrioventricular valve reintervention and risk of atrial tachyarrhythmia (AT)
Main finding
As reported in the abstract
At least one significant atrial tachyarrhythmia (AT) · median follow-up of 10.6 years
Cohort with at least one significant AT
28% (24/85)
Median onset time after anatomic repair (AR)
9.0 years
Observational data: associations, not effects.
Further findings
Long-term risk of AT with need for atrioventricular valve reintervention
| Comparison | HR (95% CI) | P value | |
|---|---|---|---|
| atrioventricular valve reintervention · increased risk of AT | 4.4 (1.4–13.8) | P = 0.01 | |
| 0.050.21520Hazard ratio (log scale) |
AT burden
- The majority of patients who experienced AT had a low disease burden
Original publication
Long-Term Electrophysiologic Comorbidities After Anatomically Repaired Congenitally Corrected Transposition of the Great Arteries. JACC Clin Electrophysiol. Published 13 August 2026. doi:10.1016/j.jacep.2026.06.019
Summarised from the published abstract; every number is checked against it