Heart failure & cardiomyopathiesCohort study
Long-Term Exposure to Road Traffic Noise and Incident Heart Failure
- Prospective cohort study
- UK Biobank
Study context
- Population
- Participants without heart failure (HF) at baseline in UK Biobank12,817 incident HF
- Participants
- 424,767 participants
- Exposure
- Higher vs lower long-term residential road traffic noise exposure
- Outcome
- Incident HF
- Follow-up
- Median 12.5 years
Main finding
As reported in the abstract
median 12.5 years
Hazard ratio (95% CI)
per 10 dB[A] increase in Lden
1.08(1.00–1.16)
Lden >65 dB[A] vs Lden ≤55 dB[A]
1.15(1.02–1.31)
Observational data: associations, not effects.
Further findings
Combined road traffic noise and air pollution (fine particles, nitrogen dioxide)
- Strongest combined effects with high exposure to both road traffic noise and air pollution
Mediation by prior acute myocardial infarction (AMI) before HF within 2 years
- Proportion of noise–HF association mediated by prior AMI
- 12.5%
- time-dependent mediation
Original publication
Long-Term Exposure to Road Traffic Noise and Incident Heart Failure. JACC Heart Fail. Published 24 May 2023. doi:10.1016/j.jchf.2023.04.003
Summarised from the published abstract; every number is checked against it