Cardio-oncology & otherCohort study
Long-term incidence of infective endocarditis according to the type of cardiac implantable electronic device: a nationwide comparison with moderate- and high-risk patient groups
- Nationwide registry-based cohort study
- Danish nationwide registries
Authors' conclusion
In this nationwide cohort, IE risk differed across CIED types, highest in CRT-D and lowest in pacemaker recipients. All CIED types were associated with higher risk than moderate-risk patients but lower risk than high-risk patients, supporting ESC classification.
Study context
- Population
- Patients with first-time cardiac implantable electronic device (CIED) implantation and reference populations at moderate and high infective endocarditis (IE) risk, Denmark, 2000–2022; CIED group excluded prior IE or left-sided prosthetic valve84,171 CIED recipients
- Exposure
- CIED types vs moderate- and high-risk IE reference groups
- Moderate-riskn = 127,966reference
- High-riskn = 23,505
- Outcome
- Incident IE
- Follow-up
- Within 10 years
Main finding
As reported in the abstract
10-year cumulative incidence of IE · 10 years
Observational data: associations, not effects.
Original publication
Long-term incidence of infective endocarditis according to the type of cardiac implantable electronic device: a nationwide comparison with moderate- and high-risk patient groups. Europace. Published 28 August 2026. doi:10.1093/europace/euag232
Summarised from the published abstract; every number is checked against it