Heart failure & cardiomyopathies
Long-Term Outcome of Myectomy Associated With Secondary Mitral Valve Chordal Cutting in Obstructive Hypertrophic Cardiomyopathy
Authors' conclusion
Our results show that cutting thickened and/or retracted secondary chordae of the anterior mitral leaflet in association with septal myectomy has excellent long-term clinical and hemodynamic results in patients with obstructive HCM.
Study context
- Population
- Patients with obstructive hypertrophic cardiomyopathy undergoing surgery over a 5-year period344 (99%) with follow-up
- Participants
- 350 patients
- Outcome
- Long-term results of myectomy with chordal cutting (overall survival)
- Follow-up
- 6 years
Methodological detailssingle-centre, consecutive patients
- Single-centre
- Consecutive patients
Main finding
As reported in the abstract
Overall survival after surgery
- 6-year overall survival after surgery
- 96%
- Did not differ from the general Italian population matched for age and sex
- P = 0.331
Observational data: associations, not effects.
Further findings
NYHA functional class at most recent evaluation
- NYHA class I (asymptomatic)
- 271 (79%)
- NYHA class II
- 65 (19%)
- NYHA class III
- 8 (2%)
Deaths during follow-up
- Deaths
- 14
- Deaths unrelated to hypertrophic cardiomyopathy (HCM)
- 6
Echocardiography at most recent evaluation
- No residual LV outflow gradient, clinically significant mitral regurgitation or impaired systolic function
- ≥95%
Surgical mortality (in-hospital deaths)
- In-hospital deaths
- 2
- Surgical mortality
- 0.6%
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Long-Term Outcome of Myectomy Associated With Secondary Mitral Valve Chordal Cutting in Obstructive Hypertrophic Cardiomyopathy. J Am Coll Cardiol. Published 17 June 2026. doi:10.
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