Heart failure & cardiomyopathiesCohort study
Long-Term Outcomes From a Decade of Donation After Circulatory Death Heart Transplantation in Australia
- Retrospective cohort study
- single-centre
- consecutive recipients
Authors' conclusion
Heart transplant recipients from DCD donors have similar survival and freedom from CAV at 10 years post HT when compared with a contemporary cohort of recipients from DBD donors.
Study context
- Population
- Consecutive heart transplant recipients, St Vincent's Hospital Sydney, July 2014 to December 2024
- Participants
- 118 vs 385
- Exposure
- DCD vs DBD heart transplantation
- DCDn = 118
- DBDn = 385reference
- Outcome
- Patient survival and freedom from CAV
- Follow-up
- 10 years
Main finding
As reported in the abstract
Hazard ratio
0.9
95% CI 0.5–1.4
P = 0.5
By group
DCD
67%
10-year survival · 10-year freedom from cardiac allograft vasculopathy (CAV) 61%
DBD
64%
10-year survival · 10-year freedom from CAV 41%
DCD vs DBD
HR 0.9 (95% CI 0.5–1.4); P = 0.5
Observational data: associations, not effects.
Further findings
1-year survival
| Outcome | OR (95% CI) | P value | |
|---|---|---|---|
| Asystolic warm ischemic time as risk factor for severe primary graft dysfunction in DCD HT · only retrieval-specific independent risk factor | 1.4 (1.1–2.0) | P = 0.03 | |
| 0.512Odds ratio (log scale) |
1-year survival
- No significant difference in short-term survival
Safety
Severe primary graft dysfunction
Severe primary graft dysfunction
- No significant difference
Original publication
Long-Term Outcomes From a Decade of Donation After Circulatory Death Heart Transplantation in Australia. JACC Heart Fail. Published 10 June 2026. doi:10.1016/j.jchf.2026.103168
Summarised from the published abstract; every number is checked against it