Heart failure & cardiomyopathiesCohort study
Long-Term Outcomes in Women With a History of Peripartum Cardiomyopathy
- Prospective cohort study
- multicentre
- 3 medical centres in Israel
Authors' conclusion
This study demonstrates favorable long-term outcomes in women with PPCM, low mortality, and stability of cardiac function.
Study context
- Population
- Women with peripartum cardiomyopathy (PPCM)96 analysed
- Participants
- 119 women
- Outcome
- Long-term outcomes of PPCM
Main finding
As reported in the abstract
- LV recovery (left ventricular ejection fraction (LVEF) ≥50%)
- 76%
- Median LVEF at 1 year
- 55% (Q1-Q3: 49%-60%)
- Median LVEF at presentation
- 38% (Q1-Q3: 30%-43%)
- LVEF at long-term follow-up
- 56% (Q1-Q3: 50%-60%)
- Deaths from noncardiac causes
- 2
- Deaths of unknown cause
- 1
- Decline in LVEF among patients with LV recovery
- 5
- LV recovery during long-term follow-up among patients with persistent LV dysfunction
- 5 of 23
- ≥1 CV medications during 10 years of follow-up
- 46%
Observational data: associations, not effects.
Further findings
Subsequent pregnancies
- Patients with subsequent pregnancies (median LVEF 58% [Q1-Q3: 55%-60%])
- 56
- Full-term deliveries
- 51
Original publication
Long-Term Outcomes in Women With a History of Peripartum Cardiomyopathy. JACC Heart Fail. Published 10 October 2025. doi:10.1016/j.jchf.2025.102702
Summarised from the published abstract; every number is checked against it