Acute cardiac care & resuscitationCohort study

Long-Term Outcomes of Cardiogenic Shock Complicating Myocardial Infarction

J Am Coll CardiolPublished

  • Retrospective cohort study
  • population-based
  • linked health administrative databases

Authors' conclusion

Short- and long-term mortality among patients with AMI-CS is high, with minimal improvement over time. AMI-CS survivors experience significant morbidity, with high risks of readmission and death.

Study context

Population
Critically ill adults with cardiogenic shock complicating acute MI (AMI-CS), Ontario, Canada, admitted April 2009–March 2019
Participants
9,789 adults · 135 centers
Outcome
Long-term outcomes of AMI-CS:
  • Mortality
  • Readmission
  • Morbidity

Main finding

As reported in the abstract

Mortality

In-hospital death

2,961 (30.2%)

Death by 1 year

4,004 (40.9%)

Mortality at 5 years

58.9%

Observational data: associations, not effects.

Further findings

Incidence of AMI-CS

Incidence (increased over the study period)
8.2 per 100,000 person-years

Critical care interventions

Invasive mechanical ventilation
5,422 (55.4%)
Renal replacement therapy
1,425 (14.6%)
Mechanical circulatory support
1,484 (15.2%)

Outcomes among survivors to discharge · 1 year after discharge

Increased support in care from preadmission baseline
2,870 (42.0%)
Readmitted within 1 year
3,244 (47.5%)
Died within 1 year
1,047 (15.3%)
Mean days at home in the year after discharge
307.9 ± 109.6

Original publication

Long-Term Outcomes of Cardiogenic Shock Complicating Myocardial Infarction. J Am Coll Cardiol. Published 5 September 2023. doi:10.1016/j.jacc.2023.06.026

Summarised from the published abstract; every number is checked against it