Valvular & structural heart diseaseCohort study
Long-Term Outcomes of Contemporary Surgical Repair for Degenerative Mitral Regurgitation
- Retrospective cohort study
- single-centre
- high-volume tertiary care center
- independently adjudicated outcomes
Authors' conclusion
This contemporary series provides further data on the low in-hospital mortality and excellent long-term outcomes of surgical mitral repair when performed in a high-volume center.
Study context
- Population
- Patients undergoing surgical mitral repair for degenerative mitral regurgitation at a tertiary care center, 2008–2017
- Participants
- 3,317 patients
- Outcome
- Long-term survival, reinterventions and HF rehospitalizations
- Follow-up
- 10 years
Main finding
As reported in the abstract
10-year survival
89.65% (95% CI 88.75%-90.55%)
Freedom from reoperation at 10 years
96.63% (95% CI 95.63%-97.63%)
10-year freedom from HF rehospitalization
92.24% (95% CI 90.62%-93.86%)
Observational data: associations, not effects.
Further findings
In-hospital mortality
- All cases (16 of 3,317)
- 0.48%
- Isolated mitral valve repair (5 of 2,399)
- 0.21%
Independent risk factors
- Survival: preoperative symptoms and anterior leaflet disease
- Reoperation: anterior leaflet disease, second run of cardiopulmonary bypass, more than mild mitral regurgitation at discharge
- HF rehospitalization: age, prior HF hospitalization, preoperative symptoms, anterior leaflet disease
Original publication
Long-Term Outcomes of Contemporary Surgical Repair for Degenerative Mitral Regurgitation. J Am Coll Cardiol. Published 5 February 2025. doi:10.1016/j.jacc.2024.10.108
Summarised from the published abstract; every number is checked against it