Cohort study
Long-term outcomes of perioperative myocardial infarction/injury after non-cardiac surgery
- Prospective cohort study
- multicentre
- central adjudication by two independent physicians
Authors' conclusion
At 1 year, most PMI aetiologies have unacceptably high rates of MACE and all-cause death
Study context
- Population
- Consecutive high-risk patients undergoing major non-cardiac surgeryPerioperative myocardial infarction/injury (PMI) in 1016 (13.1%)
- Participants
- 7,754 patients
- Exposure
- PMI aetiologies vs no PMI
- Outcome
- MACE (acute MI, AHF [both from day 3], life-threatening arrhythmia, CV death) and all-cause death
- Follow-up
- 1 year
Main finding
As reported in the abstract
MACE and all-cause death by PMI aetiology
| Group | MACE | Death |
|---|---|---|
| Extra-cardiac PMI | 51% | 38% |
| T1MI | 41% | 27% |
| Tachyarrhythmia | 57% | 40% |
| Acute heart failure (AHF) | 64% | 49% |
| lT2MI | 25% | 17% |
| No PMI | 7% | 9% |
Observational data: associations, not effects.
Further findings
MACE and all-cause death, whole cohort · 1 year
- At least one MACE
- 684/7754 (8.8%)
- All-cause death
- 818/7754 (10.5%)
Original publication
Long-term outcomes of perioperative myocardial infarction/injury after non-cardiac surgery. Eur Heart J. Published 27 January 2023. doi:10.1093/eurheartj/ehac798
Summarised from the published abstract; every number is checked against it