Prevention & lipidsCohort study

Long-term physical activity time-in-target range in young adults with cardiovascular events in later life

Eur J Prev CardiolPublished

  • Prospective cohort study

Authors' conclusion

In young adults, maintaining long-term guidelines-recommended PA levels may help to lower the risk of cardiovascular events in later life.

Study context

Population
Young adults in the Coronary Artery Risk Development in Young Adults study; Time-in-target range (TTR) estimated across the first 15 years
Participants
2,902 adults
Exposure
Physical activity (PA) TTR categories during young adulthood
  • <25%n = 1,028reference
  • 25 to <50%n = 444
  • 50 to <75%n = 424
  • 75 to 100%n = 1,006
Outcome
Composite of CV events
Follow-up
Median 18.9 years after exposure period

Main finding

As reported in the abstract

Hazard ratio (95% CI)
75 to 100% vs <25%
0.60(0.38–0.95)
Each 1-SD increase in TTR
0.79(0.65–0.97)

Observational data: associations, not effects.

Original publication

Long-term physical activity time-in-target range in young adults with cardiovascular events in later life. Eur J Prev Cardiol. Published 20 December 2023. doi:10.1093/eurjpc/zwad403

Summarised from the published abstract; every number is checked against it