Coronary disease & ACSCohort study
Long-Term Prognosis of Acute Myocardial Infarction Caused by Isolated Diffuse Coronary Artery Ectasia
- retrospective
Authors' conclusion
The patients with MI due to isolated CAE had a higher risk of recurrent MI and stent thrombosis compared with the patients without CAE. In this study, the rate of recurrent MI from the index infarct artery was also higher in the patients with CAE.
Study context
- Population
- Patients who underwent coronary angiography with a diagnosis of first myocardial infarction (MI) caused by isolated coronary artery ectasia (CAE), and patients with MI without CAE as controlspatients included
- Participants
- 404 patients
- Exposure
- patients with myocardial infarction (MI) due to isolated CAE with the patients without CAE
- Outcome
- composite of:
- All-cause death
- Nonfatal recurrent MI occurring after index hospitalization
Main finding
As reported in the abstract
Hazard ratio
1.84
95% CI 1.11–3.05
P = 0.017
Events by group
isolated CAE group vs control group
hazard ratio 1.84 (95% CI 1.11–3.05); P = 0.017
Observational data: associations, not effects.
Further findings
Death
| Outcome | isolated CAE group | control group | hazard ratio (95% CI) | P value | |
|---|---|---|---|---|---|
| Recurrent MI · multiple variable analysis; presence of CAE | 22.8% | 13.4% | 2.07 (1.08–3.96) | P = 0.029 | |
| 0.20.5125Hazard ratio (log scale) |
ST-elevation MI
- MIs that were ST-elevation MI, overall
- 63.9%
Ectasia classification in isolated CAE group
- Markis I
- 71.3%
- Markis II
- 26.7%
- Almost all had multivessel diffuse ectasia
Safety
Stent thrombosis · more common in the CAE group
P < 0.001
Original publication
Long-Term Prognosis of Acute Myocardial Infarction Caused by Isolated Diffuse Coronary Artery Ectasia. Circ Cardiovasc Interv. Published 6 February 2026. doi:10.1161/circinterventions.125.016071
Summarised from the published abstract; every number is checked against it