Long-term prognostic value of contemporary stress echocardiography in patients with suspected or known coronary artery disease: systematic review and meta-analysis
Pooled result · MACEResult — go to the resultOdds ratio 2.04 95% CI 1.79–2.33Authors' conclusion
Positive stress echocardiography results were associated with poorer long-term MACE and all-cause mortality.
Study context
- Population
- Patients with suspected or known CAD undergoing pharmacological or treadmill stress echocardiography, studies since 2000
- Participants
- 16,581 patients · 6 trials
- Comparison
- Positive vs negative stress echocardiography
- Outcome
- MACE:
- All-cause mortality or CV death and non-fatal MI
- Per trial definition
- Follow-up
- Median 31 months (range 21-101)
Methodological detailscommon-effect model
- Common-effect model
Pooled result
MACE
Odds ratio
2.04
95% CI 1.79–2.33
By group
Positive stress echocardiography vs Negative stress echocardiography
OR 2.04 (95% CI 1.79–2.33)
As reported in the abstract
Further pooled results
Annual event rate
| Outcome | Positive stress echocardiography | Negative stress echocardiography | OR (95% CI) | |
|---|---|---|---|---|
| All-cause mortality | 1.68% | 1.02% | 2.06 (1.80–2.35) | |
| 0.512Odds ratio (log scale) |
Overall annual event rates (all patients)
- Major adverse cardiovascular event (MACE) annual event rate
- 1.76%
- All-cause mortality annual event rate
- 1.35%
Original publication
Long-term prognostic value of contemporary stress echocardiography in patients with suspected or known coronary artery disease: systematic review and meta-analysis. Heart. Published 23 August 2024. doi:10.
Summarised from the published abstract; every number is checked against it