Cohort study
Long-term pulse pressure trajectories and risk of incident atrial fibrillation: the Tromsø Study
- Prospective cohort study
- population-based
- group-based trajectory modelling
Authors' conclusion
Long-term elevated pulse pressure trajectories were independently associated with increased risk of AF in women, but not in men.
Study context
- Population
- Women and men aged ≥20 years attending ≥2 of 3 Tromsø Study surveys 1986–2001, followed for incident atrial fibrillation (AF) through 2016women n = 8331
- Exposure
- Long-term pulse pressure trajectory groups
- Outcome
- Incident AF
- Follow-up
- Throughout 2016
Main finding
As reported in the abstract
Incident AF in women
Each group vs group 1Adjusted hazard ratio (95% CI)
Group 2
1.60(1.23–2.09)
Group 3
2.78(1.93–4.02)
Observational data: associations, not effects.
Further findings
Incident AF over follow-up, by sex
Original publication
Long-term pulse pressure trajectories and risk of incident atrial fibrillation: the Tromsø Study. Eur Heart J. Published 17 January 2025. doi:10.1093/eurheartj/ehaf005
Summarised from the published abstract; every number is checked against it