Long-Term Risk of Cardiovascular Disease in Women Who Have Had Infants With Heart Defects
Authors' conclusion
Women whose infants have congenital heart defects have a greater risk of cardiovascular hospitalization later in life.
Study context
- Population
- Women who delivered infants between 1989 and 2013 in Quebec, Canada
- Participants
- 1,084,251 women
- Exposure
- Infant critical or noncritical heart defects vs no heart defects
- Outcome
- Maternal CV hospitalization
- Follow-up
- Up to 25 years past pregnancy
Methodological detailspopulation-based
- Population-based
Main finding
As reported in the abstract
Any CV hospitalization
Each group vs no heart defectsHazard ratio (95% CI)
Critical defects
1.43(1.13–1.82)
Noncritical defects
1.24(1.15–1.34)
Observational data: associations, not effects.
Further findings
Specific causes of CV hospitalization (MI, HF, other atherosclerotic disorders)
- Greater risks for mothers of infants with congenital heart defects than with no defects
Original publication
Long-Term Risk of Cardiovascular Disease in Women Who Have Had Infants With Heart Defects. Circulation. Published 2 April 2018. doi:10.
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