Arrhythmias & electrophysiologyCohort study

Long-Term Risk of Heart Failure in Patients with Postoperative Atrial Fibrillation Following Non-Cardiac Surgery: Insights from a Nationwide Cohort

Eur J Heart FailPublished

  • Retrospective cohort study
  • nationwide registries
  • matched cohort (1:3)

Authors' conclusion

Patients with new-onset POAF following non-cardiac surgery had a higher associated long-term rate of incident HF compared to those without POAF, with no significant difference in the rate of incident HF when compared to patients with NVAF.

Study context

Population
Patients aged ≥30 years undergoing non-cardiac surgery, Danish nationwide registries, 1996–2020Postoperative AF (POAF) 2270 vs No POAF
Exposure
POAF vs No POAF vs non-valvular AF (NVAF)
  • No POAFn = 6,810reference
  • NVAFn = 5,538reference
Outcome
Long-term rate of incident heart failure (HF)
Follow-up
Median 7.2 years

Main finding

As reported in the abstract

Incident HF
Adjusted hazard ratio (95% CI)
POAF vs No POAF2.6 vs. 1.2 events per 100 person-years
2.39(2.06–2.78)
POAF vs NVAF2.7 vs. 3.0 events per 100 person-years
0.89(0.78–1.03)

Observational data: associations, not effects.

Original publication

Long-Term Risk of Heart Failure in Patients with Postoperative Atrial Fibrillation Following Non-Cardiac Surgery: Insights from a Nationwide Cohort. Eur J Heart Fail. Published 12 November 2024. doi:10.1002/ejhf.3518

Summarised from the published abstract; every number is checked against it