Valvular & structural heart diseaseCohort study
Long-Term Risk of Stroke After Transcatheter Aortic Valve Replacement
- Registry-based cohort study
- consecutive patients
- national registry (SwissTAVI)
Authors' conclusion
Compared with an age- and sex-matched population, TAVR patients experienced a higher risk of stroke for up to 2 years after the procedure, and a comparable risk thereafter.
Study context
- Population
- Consecutive patients undergoing transcatheter aortic valve replacement (TAVR) in Switzerland, February 2011 to June 2021
- Participants
- 11,957 patients
- Exposure
- TAVR population vs age- and sex-matched Swiss general population
- TAVRn = 11,957
- Outcome
- Short- and long-term incidence of stroke after TAVR; Standardized stroke ratios (SSRs) vs matched general population
Main finding
As reported in the abstract
Stroke incidence after TAVR
TAVR
3.0%
30-day cumulative incidence · 1-year incidence 4.3% · 5-year incidence 7.8%
SSR
- first year, males
- 7.26 (95% CI 6.3–8.36)
- first year, females
- 6.82 (95% CI 5.97–7.79)
- second year, males
- 1.98 (95% CI 1.47–2.67)
- second year, females
- 1.48 (95% CI 1.09–2.02)
Observational data: associations, not effects.
Original publication
Long-Term Risk of Stroke After Transcatheter Aortic Valve Replacement. JACC Cardiovasc Interv. Published 25 December 2023. doi:10.1016/j.jcin.2023.10.021
Summarised from the published abstract; every number is checked against it