Long-Term Road Traffic Noise, Air Pollution, and Cardiovascular Disease: AIRCARD: A Prospective Cohort Study
Main finding · Major adverse cardiovascular eventsResult — go to the resultHazard ratio 1.075 95% CI 1.026–1.128Authors' conclusion
Long-term exposure to road traffic noise was significantly associated with increased CVD and all-cause mortality. Our findings suggest that studies that do not consider noise exposure may overestimate the cardiovascular burden attributed to air pollution. (Impact of Lifetime Exposure to Air and Noise Pollution on Cardiovascular Disease and Mortality-the AIRCARD Study [AIRCARD]; NCT04353232).
Study context
- Population
- Men aged 65 to 74 years from the DANCAVAS (Danish Cardiovascular Screening Trial) (2014–2018) and VIVA (Viborg vascular) (2008–2010) screening trials, with pollution exposure data from 1979 to 2019men aged 65 to 74 years
- Participants
- 26,723 men
- Exposure
- Long-term residential exposure to air pollutants (particulate matter with a diameter <2.5 μm, nitrogen dioxide, warm-season ozone, sulfur dioxide, and carbon monoxide) and road traffic noise (Lden), and cardiovascular disease (CVD)
- Outcome
- Major adverse cardiovascular events
Main finding
As reported in the abstract
Hazard ratio
1.075
95% CI 1.026–1.128
14.9 decibel increase in road traffic noise (IQR increment)
HR 1.075 (95% CI 1.026–1.128)
Observational data: associations, not effects.
Secondary outcomes
All-cause mortality
| HR (95% CI) | ||
|---|---|---|
| 14.9 decibel increase in road traffic noise (IQR increment)8.1% increased risk | 1.081 (1.027–1.137) | |
| 0.512Hazard ratio (log scale) |
Air pollutants and primary or secondary outcomes
- No significant associations in the pooled cohort after adjustment for confounders
Original publication
Long-Term Road Traffic Noise, Air Pollution, and Cardiovascular Disease: AIRCARD: A Prospective Cohort Study. JACC Adv. Published 21 May 2025. doi:10.
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