Coronary disease & ACS

Long-term survival after surgical treatment for post-infarction mechanical complications: results from the Caution study

Eur Heart J Qual Care Clin OutcomesPublished Retrospective cohort study

Authors' conclusion

Contemporary data from a multicentre cohort study show that surgical treatment for post-AMI MCs continues to be associated with high in-hospital mortality rates. However, long-term survival in patients surviving the immediate post-operative period is encouraging.

Study context

Population
Patients undergoing surgical treatment for post-infarction mechanical complications, 2001–2019
Participants
720 patients
Outcome
In-hospital and long-term mortality
Methodological detailsmulticentre, 27 centres worldwide
  • Multicentre
  • 27 centres worldwide

Main finding

As reported in the abstract

In-hospital mortality
37.4%
Late mortality (median follow-up 4.4 [1.0-8.6] years)
133 patients
Overall survival at 1 year
54.0%
Overall survival at 5 years
48.1%
Overall survival at 10 years
41.0%

Observational data: associations, not effects.

Further findings

Independent predictors of overall mortality

Older age
P < 0.001
Post-operative low cardiac output syndrome
P < 0.001

10-year survival in hospital survivors

10-year survival, hospital survivors
65.7%
Higher with ventricular septal rupture than papillary muscle rupture
P = 0.022
  • Log-rank P (printed "long-rank")

Original publication

Long-term survival after surgical treatment for post-infarction mechanical complications: results from the Caution study. Eur Heart J Qual Care Clin Outcomes. Published 7 February 2024. doi:10.1093/ehjqcco/qcae010

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