Long-Term Survival and Freedom From Reintervention After Off-Pump Coronary Artery Bypass Grafting: A Propensity-Matched Study
Main finding · Death or reintervention (composite)Result — go to the resultHR for death or reintervention 0.98 95% CI 0.92–1.06Authors' conclusion
OPCAB is associated with similar long-term outcomes to CABG performed on CPB in our institution.
Study context
- Population
- All isolated coronary artery bypass grafting (CABG) at one institution, 2001–2015
- Participants
- 13,226 participants
- Exposure
- Off-pump CABG vs CABG on cardiopulmonary bypass
- OPCABn = 5,882
- Cardiopulmonary bypass (CPB)n = 7,344reference
- Outcome
- Long-term composite of:
- Death
- Revascularisation
- Follow-up
- Median 6.2 years
Methodological detailspropensity-score matched, single-centre
- Propensity-score matched
- Single-centre
Main finding
Death or reintervention (composite)
HR for death or reintervention
0.98
95% CI 0.92–1.06
P = 0.23
OPCAB vs CPB
HR for death or reintervention 0.98 (95% CI 0.92–1.06); P = 0.23
As reported in the abstract
Observational data: associations, not effects.
Further findings
| Outcome | OPCAB | CPB | Adjusted HR for death (95% CI) | P value | |
|---|---|---|---|---|---|
| Long-term survival (death) | 1.03 (0.94–1.11) | P = 0.56 | |||
| 1-year survival | 96.7% | 96.2% | |||
| 5-year survival | 87.9% | 87.4% | |||
| 10-year survival | 72.1% | 72.8% | |||
| 0.512Adjusted HR for death (log scale) |
Safety
Complications (such as MI)
- Fewer complications with OPCAB
Original publication
Long-Term Survival and Freedom From Reintervention After Off-Pump Coronary Artery Bypass Grafting: A Propensity-Matched Study. Circulation. Published 25 October 2016. doi:10. 1161/ circulationaha. 116. 021933
Summarised from the published abstract; every number is checked against it