Long-Term Survival and Freedom From Reintervention After Off-Pump Coronary Artery Bypass Grafting: A Propensity-Matched Study

CirculationPublished Retrospective cohort study

Main finding · Death or reintervention (composite)Result — go to the resultHR for death or reintervention 0.98 95% CI 0.92–1.06

Authors' conclusion

OPCAB is associated with similar long-term outcomes to CABG performed on CPB in our institution.

Study context

Population
All isolated coronary artery bypass grafting (CABG) at one institution, 2001–2015
Participants
13,226 participants
Exposure
Off-pump CABG vs CABG on cardiopulmonary bypass
  • OPCABn = 5,882
  • Cardiopulmonary bypass (CPB)n = 7,344reference
Outcome
Long-term composite of:
  • Death
  • Revascularisation
Follow-up
Median 6.2 years
Methodological detailspropensity-score matched, single-centre
  • Propensity-score matched
  • Single-centre

Main finding

Death or reintervention (composite)

HR for death or reintervention

0.98

95% CI 0.92–1.06

P = 0.23

OPCAB vs CPB
HR for death or reintervention 0.98 (95% CI 0.92–1.06); P = 0.23

As reported in the abstract

Observational data: associations, not effects.

Further findings

OutcomeOPCABCPBAdjusted HR for death (95% CI)P value
Long-term survival (death)1.03 (0.94–1.11)P = 0.56
1-year survival96.7%96.2%
5-year survival87.9%87.4%
10-year survival72.1%72.8%

Safety

Complications (such as MI)

Fewer complications with OPCAB

Original publication

Long-Term Survival and Freedom From Reintervention After Off-Pump Coronary Artery Bypass Grafting: A Propensity-Matched Study. Circulation. Published 25 October 2016. doi:10.1161/circulationaha.116.021933

Summarised from the published abstract; every number is checked against it

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