Acute cardiac care & resuscitation
Long-Term Survival Following Extracorporeal Cardiopulmonary Resuscitation: A Two-Center Five-Year Analysis
Authors' conclusion
Among patients discharged alive after ECPR for refractory OHCA, long-term survival was substantial, with approximately two-thirds alive at 5 years with favorable CPC in most. Younger age and discharge home or to acute rehabilitation identified subgroups with particularly favorable prognosis. These findings support the long-term durability of benefit among selected patients treated within established ECPR systems of care.
Study context
- Population
- Patients discharged alive after extracorporeal cardiopulmonary resuscitation (ECPR) for refractory VT/VF out-of-hospital cardiac arrest (OHCA) from two academic centers (University of Minnesota, USA, and Charles University, Prague) from January 2013 through December 2022survived to discharge (29.0%), among 728 patients treated with ECPR · Minnesota 138 · Prague 73
- Participants
- 211 patients
- Outcome
- 5-year survival
- Follow-up
- 5 years
Methodological detailsconsecutive patients, two academic centers
- Consecutive patients
- Two academic centers
Main finding
As reported in the abstract
Alive at 5 years, among hospital survivors
67.2%
Observational data: associations, not effects.
Secondary outcomes
Conduct of follow-up
- Median follow-up was 3.9 years
- 68 patients (32%) completed 5 years
- No patients were lost to follow-up
Survival at 1 year
- Alive at 1 year, among hospital survivors
- 76.9%
- Most deaths occurring within 90 days of discharge
Neurological status by Cerebral Performance Category (CPC)
- CPC 1-2 at discharge
- 78.7%
- CPC 1-2 among survivors beyond 1 year
- 93.4%-94.2%
Five-year survival by age · 5 years
- 18-39 years
- 91.6%
- >70 years
- 52.9%
Long-term prognosis by discharge disposition
- Discharge disposition also strongly stratified long-term prognosis
Original publication
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