Coronary disease & ACSResearch article
Low ambient temperature and incident myocardial infarction with or without obstructive coronary arteries: a Chinese nationwide study
- Case-crossover study
- nationwide
- time-stratified
- distributed lag non-linear models (10 days)
Authors' conclusion
This nationwide study highlights the particular susceptibility of MINOCA patients to ambient low temperature compared with that of MI-CAD patients.
Study context
- Population
- Patients with MI in the Chinese Cardiovascular Association database-Chest Pain Center Registry, 2015–2021
- Participants
- 83,784 vs 918,730
- Comparison
- Extremely low vs reference ambient temperature, myocardial infarction with non-obstructive coronary arteries (MINOCA) vs MI-CAD
- MINOCAn = 83,784
- MI-CADn = 918,730
- Outcome
- Association of ambient temperature with onset of MINOCA and MI-CAD
Main finding
As reported in the abstract
MI onset with extremely low temperature
Odds ratio (95% CI)
MINOCAextremely low vs reference temperature (30°C)
1.58(1.31–1.90)
MI-CADunmatched; vs reference temperature (35°C)
1.32(1.23–1.43)
MI-CADequally matched by age and sex; vs reference temperature (30°C)
1.25(1.04–1.50)
Further findings
Subgroups
- Stronger associations in patients aged ≥65 years, female, or residing in the south
High temperature
- No significant difference for impacts of high temperature on MINOCA and MI-CAD
Original publication
Low ambient temperature and incident myocardial infarction with or without obstructive coronary arteries: a Chinese nationwide study. Eur Heart J. Published 28 October 2024. doi:10.1093/eurheartj/ehae711
Summarised from the published abstract; every number is checked against it