Acute cardiac care & resuscitationCohort study
Lung Ultrasound and Mortality in a Cardiogenic Shock Population: A Prospective Registry-Based Analysis
- Prospective registry-based cohort study
- multicentre
- observational registry
Authors' conclusion
Assessment and monitoring of lung congestion with LUS over the first 24 h in patients with CS allow to further stratify clinical outcomes with higher accuracy when added to SCAI classification, especially when excluding patients with cardiac arrest at CS presentation.
Study context
- Population
- All-comer patients with cardiogenic shock (Altshock-2 registry)Lung ultrasound (LUS) at admission
- Participants
- 185 patients
- Exposure
- B-lines ≥50% vs <50% of investigated lung field on LUS
- Outcome
- 30-day mortality
- Follow-up
- 30 days
Main finding
As reported in the abstract
Hazard ratio (95% CI)P value
B-lines ≥50% at 24 hunivariate Cox
4.705(2.329–9.508)
Reduction of B-lines during 24 hunivariate Cox
0.739(0.571–0.956)
P = 0.021B-lines ≥50% at 24 hmultivariate, adjusted
2.23(1.042–8.654)
P = 0.041Reduction in B-lines from baseline to 24 hmultivariate, adjusted
0.815(0.415–1.132)
P = 0.039Observational data: associations, not effects.
Further findings
Prevalence of lung congestion at admission
- ≥50% of investigated lung field with B-lines
- 128 patients (69.2%)
Sensitivity analysis excluding cardiac arrest
- Significantly increased accuracy in outcome prediction
Original publication
Lung Ultrasound and Mortality in a Cardiogenic Shock Population: A Prospective Registry-Based Analysis. Eur J Heart Fail. Published 30 May 2025. doi:10.1002/ejhf.3692
Summarised from the published abstract; every number is checked against it