Cardiometabolic & kidney

Machine Learning for Predicting Long-Term Cardiovascular Outcomes in Kidney Transplant Recipients

JACC AdvPublished Retrospective cohort study

Authors' conclusion

ML models are feasible for predicting cardiovascular events in KTRs.

Study context

Population
Adult kidney transplant recipients, single centre, 2015–2024102 with MACE
Participants
518 recipients
Exposure
CatBoost machine learning (ML) model vs multivariable logistic regression vs Soveri risk score
Outcome
Prediction of MACE
Follow-up
Mean 5.3 ± 2.3 years
Methodological detailssingle-centre, machine learning prediction model development
  • Single-centre
  • Machine learning prediction model development

Main finding

As reported in the abstract

MACE prediction
GroupAUROCArea under precision-recall curve
CatBoost0.72 (95% CI: 0.607-0.811)0.36 (95% CI: 0.230-0.540)
Logistic regression0.67 (95% CI: 0.559-0.772)0.31 (95% CI: 0.228-0.553)

AUROC

CatBoost0.72 (95% CI: 0.607-0.811)
Logistic regression0.67 (95% CI: 0.559-0.772)

Area under precision-recall curve

CatBoost0.36 (95% CI: 0.230-0.540)
Logistic regression0.31 (95% CI: 0.228-0.553)

Observational data: associations, not effects.

Further findings

Top predictive variables

CAD, left atrial reservoir strain, dialysis duration, LV end-diastolic volume index

Original publication

Machine Learning for Predicting Long-Term Cardiovascular Outcomes in Kidney Transplant Recipients. JACC Adv. Published 18 November 2025. doi:10.1016/j.jacadv.2025.102364

Composed by AI from the published abstract and checked against it. How Briefs are made →

Get them every week

New studies on this topic in My Week and in your Monday e-mail.

We e-mail you a sign-in link and a code. No password, no spam.