Arrhythmias & electrophysiologyCohort study
Magnetic resonance detection of advanced atrial cardiomyopathy increases the risk for atypical atrial flutter occurrence following atrial fibrillation ablation
- Cohort study from a prospective registry
- consecutive patients
Authors' conclusion
Advanced atrial cardiomyopathy assessed by LGE-CMR, such as increased LA sphericity, global LA fibrosis, and fibrosis in the lateral wall, is independently associated with arrhythmia recurrence in the form of AFL following AF ablation.
Study context
- Population
- Patients with AF recurrence after catheter ablation with baseline LGE-CMR, requiring re-ablationfrom registry cohort of 1007
- Participants
- 166 patients
- Exposure
- Atrial flutter (AFL) recurrence vs AF recurrence after AF ablation
- AFLn = 56
- AFn = 110reference
- Outcome
- Occurrence of atypical AFL after AF ablation
Main finding
As reported in the abstract
Independent predictors of AFL recurrence
- Age >65
- OR 5.6 (95% CI 2.2-14.4)
- Number of previous ablations
- OR 3.0 (95% CI 1.2-7.8)
- Management of ablation lines in index procedure
- OR 2.5 (95% CI 1.0-6.3)
- Enhanced left atrial (LA) sphericity on LGE-CMR
- OR 1.3 (95% CI 1.1-1.6)
- LA global fibrosis on LGE-CMR
- OR 1.03 (95% CI 1.01-1.07)
- Increased lateral wall fibrosis on LGE-CMR
- OR 1.03 (95% CI 1.01-1.04)
Observational data: associations, not effects.
Original publication
Magnetic resonance detection of advanced atrial cardiomyopathy increases the risk for atypical atrial flutter occurrence following atrial fibrillation ablation. Europace. Published 26 September 2023. doi:10.1093/europace/euad276
Summarised from the published abstract; every number is checked against it