Valvular & structural heart diseaseCohort study
Malnutrition and Outcomes in Patients with Tricuspid Regurgitation Undergoing Transcatheter Tricuspid Valve Repair
- Registry-based cohort study
- multicentre
- multivariable-adjusted
- inverse probability of treatment weighting
Authors' conclusion
In the large, real-world, multicentre EuroTR registry, malnutrition was present in one out of five patients with symptomatic TR undergoing T-TEER and was independently associated with increased mortality.
Study context
- Population
- Patients with symptomatic tricuspid regurgitation (TR) undergoing tricuspid transcatheter edge-to-edge repair (T-TEER), EuroTR registry, March 2016–February 2024
- Participants
- 1,034 patients
- Exposure
- Malnutrition vs no malnutrition
- Malnutritionn = 211
- Outcome
- All-cause mortality
Main finding
All-cause death · 2 years
Adjusted hazard ratio
1.53
95% CI 1.11–2.10
P = 0.009
By group
Malnutrition vs No malnutrition
adjusted HR 1.53 (95% CI 1.11–2.10); P = 0.009
As reported in the abstract
Observational data: associations, not effects.
Further findings
Mortality with residual TR ≤2+ vs ≥3+, by malnutrition (subgroup)
- Residual TR ≤2+ associated with a similar lower risk of mortality in patients with and without malnutrition
- interaction p = 0.947
Original publication
Malnutrition and Outcomes in Patients with Tricuspid Regurgitation Undergoing Transcatheter Tricuspid Valve Repair. Eur J Heart Fail. Published 20 February 2025. doi:10.1002/ejhf.3623
Summarised from the published abstract; every number is checked against it