Acute cardiac care & resuscitationResearch article
Management and Outcomes of Society for Cardiovascular Angiography and Interventions Stage B Cardiogenic Shock
- Multivariable analysis and mixed-effects regression models
- 6-hospital system
Authors' conclusion
Among patients with SCAI stage B cardiogenic shock, a quarter of the population experienced clinical deterioration. Acute kidney injury and diuretic resistance in the preceding 24 hours were independently predictive of developing the primary end point.
Study context
- Population
- Adult patients (≥18 years) admitted to the medical, intermediate, and critical care units who developed SCAI stage B cardiogenic shock, 2017 to 2022patients who developed SCAI stage B cardiogenic shock
- Participants
- 500 patients
- Comparison
- Deterioration cohort vs those who recovered
- deterioration cohortn = 135
- Outcome
- Composite of:
- Transfer to a higher level of care
- SCAI stage escalation
- In-hospital mortality
Main finding
As reported in the abstract
Primary composite end point noted in patients
135
Further findings
Pre-outcome characteristics
renal injury
hepatic injury
fluid balance deterioration cohort −0.30 L · those who recovered −0.68 L
diuretic resistance
- Pre-outcome characteristics: diuretic resistance P <0.001
Etiologies
- heart failure
- 37%
- arrhythmia
- 23%
- acute myocardial infarction
- 13%
Pre-outcome characteristics
- Lower blood pressures in the deterioration cohort
Predictors of clinical deterioration
- acute kidney injury adjusted odds ratio (95% CI, 1.11-4.22); P =0.02
- 2.17
- diuretic resistance adjusted odds ratio (95% CI, 2.61-34.89); P =0.001
- 9.55
- multivariable analysis
Isolated hypotension vs isolated hypoperfusion
- Patients with isolated hypotension had worse outcomes compared with those with isolated hypoperfusion
Original publication
Management and Outcomes of Society for Cardiovascular Angiography and Interventions Stage B Cardiogenic Shock. Circ Heart Fail. Published 19 February 2026. doi:10.1161/circheartfailure.125.013814
Summarised from the published abstract; every number is checked against it