Arrhythmias & electrophysiologyCohort study
Management of Lead-Related Superior Vena Cava Syndrome
- Retrospective case series
- Mayo Clinic sites
- 2014–2025
Authors' conclusion
Effective management of TVL-associated SVC syndrome involves venoplasty with or without transvenous lead extraction, showing good medium-term outcomes. Reimplantation of the device with TVL requires careful consideration, and efforts should be made to consider a leadless device when feasible.
Study context
- Population
- Patients with lead-related superior vena cava syndrome28 leads present in 14 patients
- Participants
- 14 patients
Main finding
As reported in the abstract
Median age (Q1-Q3: 45.8-66.8) years
61.0
Female
50%
Median number of leads implanted per patient (Q1-Q3: 1-2)
2.0
Median age of the leads (Q1-Q3: 31.8-74.0) months
48.0
Observational data: associations, not effects.
Further findings
Extraction procedure
- Patients who underwent extraction
- 11 patients (78.6%)
- All had complete procedural success without complications
Venoplasty and stenting
- Underwent venoplasty
- 7
- Underwent stenting
- 7
Recurrent symptomatic stenosis · median follow-up of 22.1 (Q1-Q3: 9.5-66.3) months
- Recurrent symptomatic stenosis
- 5 patients (35.7%)
- Of these, with index balloon venoplasty
- 2
- Of these, with index transvenous lead extraction and venoplasty
- 3
Device reimplantation among the 11 patients who underwent extraction
- Of the 11 extracted, required reimplantation
- 6
- Transvenous
- 2
- Epicardial
- 2
- Subcutaneous
- 1
- Leadless
- 1
Original publication
Summarised from the published abstract; every number is checked against it