Arrhythmias & electrophysiology

Marshall-Plan ablation strategy versus pulmonary vein isolation in persistent atrial fibrillation: Clinical trial design

Am Heart JPublished multicenter, prospective, randomized, parallel- group, controlled clinical trial of superiority

Study context

Population
Patients with persistent atrial fibrillation (AF)planned number of patients to be randomized
Participants
262 patients
Planned comparison
Marshall-Plan approach vs pulmonary veins isolation (PVI) approach
Primary endpoint
Freedom from any arrhythmia AF/AT <30 seconds) after a single ablation procedure with or without antiarrhythmic medication
Follow-up
2-year
Methodological detailsnine tertiary care centers across Europe (8 centers in France, 1 center in Belgium), trial design
  • Nine tertiary care centers across Europe (8 centers in France, 1 center in Belgium)
  • Trial design

No results yet. This paper sets out the design of a trial; its results are to come.

Original publication

Marshall-Plan ablation strategy versus pulmonary vein isolation in persistent atrial fibrillation: Clinical trial design. Am Heart J. Published 6 April 2026. doi:10.1016/j.ahj.2026.107442

Summarised from the published abstract; every number is checked against it

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