Arrhythmias & electrophysiologyTrial design
Marshall-Plan ablation strategy versus pulmonary vein isolation in persistent atrial fibrillation: Clinical trial design
- multicenter, prospective, randomized, parallel- group, controlled clinical trial of superiority
- nine tertiary care centers across Europe (8 centers in France, 1 center in Belgium)
- trial design
Study context
- Population
- Patients with persistent atrial fibrillation (AF)planned number of patients to be randomized
- Participants
- 262 patients
- Planned comparison
- Marshall-Plan approach vs pulmonary veins isolation (PVI) approach
- Primary endpoint
- Freedom from any arrhythmia AF/AT <30 seconds) after a single ablation procedure with or without antiarrhythmic medication
- Follow-up
- 2-year
No results yet. This paper sets out the design of a trial; its results are to come.
Original publication
Marshall-Plan ablation strategy versus pulmonary vein isolation in persistent atrial fibrillation: Clinical trial design. Am Heart J. Published 6 April 2026. doi:10.1016/j.ahj.2026.107442
Summarised from the published abstract; every number is checked against it