Cardiometabolic & kidneyResearch article

Maternal Mortality and Cardio-Kidney-Metabolic Risk Factors Across High-Income Countries

JACC AdvPublication date not resolved

  • Global Burden of Disease 2023 data

Authors' conclusion

The U.S. women of reproductive age face a disproportionate burden of CVD, CKM factors, and maternal mortality rates compared with other high-income countries. Integrating early CVD and CKM screening and management into U.S. health care should be an urgent national priority.

Study context

Population
Women of reproductive age (15–49 years) in the United States compared with other high-income countries, 2003 to 2023
Comparison
the United States compared with other high-income countries

Main finding

As reported in the abstract

CVD prevalence · 2003 to 2023

United States

3.7% to 3.1%

Further findings

OutcomeUnited Statesother high-income countries
CVD DALY rates · 2003 to 2023decline by 20%Not reported in the abstract
Maternal mortality rates · 2023 · highest compared to other high-income countries33.8 per 100,000 live birthsNot reported in the abstract
Mortality rates attributed to hypertensive disorders of pregnancy · 2023 · highest compared to other high-income countries2.8 per 100,000 live birthsNot reported in the abstract
  • Maternal mortality rates: Southern Latin America 65.2 per 100,000 live births
  • Mortality rates attributed to hypertensive disorders of pregnancy: Southern Latin America 8.9 per 100,000 live births

Cardiovascular disease (CVD) DALY rates · 2003 to 2023

CVD burden remained higher than in other high-income countries

DALY rates attributable to cardio-kidney-metabolic (CKM) risk factors

body mass index >21 kg/m², United States vs other high-income countries
4-fold higher
fasting plasma glucose >95 mg/dL, United States vs other high-income countries
3-fold higher
systolic blood pressure >115 mm Hg, United States vs other high-income countries
2-fold higher

Original publication

Maternal Mortality and Cardio-Kidney-Metabolic Risk Factors Across High-Income Countries. JACC Adv. doi:10.1016/j.jacadv.2026.102803

Summarised from the published abstract; every number is checked against it