Pulmonary vascular disease & thromboembolismRandomised controlled trial
Mechanical Thrombectomy Versus Anticoagulation Alone in Intermediate-High Risk Pulmonary Embolism (PE)
- Randomised trial
- international
- 22 sites
Authors' conclusion
In STORM-PE, CAVT with anticoagulation resulted in improved functional outcomes at 90 days compared with anticoagulation alone, with equivalent safety rates. This trial supports CAVT as an effective and safe reperfusion strategy for intermediate-high risk PE.
Study context
- Population
- Acute intermediate-high risk PEmedian follow-up 91.0 days
- Participants
- 100 participants
- Comparison
- Computer-assisted vacuum thrombectomy (CAVT) with anticoagulation vs anticoagulation alone
- Primary endpoint
- Right-ventricular (RV)-to-left-ventricular (RV/LV) ratio change
- Follow-up
- 48 hours
Reported results (secondary endpoints)
As reported in the abstract
The primary endpoint is not reported in this abstract; these are its secondary endpoints.
6-min walk distance · 90 days
P = 0.003
NYHA Functional Class I · 90 days
P = 0.005
- 6-min walk distance: longer 6-min walk distance with CAVT; completed by 66.0% (31/47) vs 64.2% (34/53)
Dyspnea and quality of life (QoL) scores · 90 days
- Dyspnea and QoL scores
- comparable between groups
All-cause mortality, PE-related mortality, and symptomatic PE recurrence · within 90 days
- All-cause mortality, PE-related mortality, and symptomatic PE recurrence
- no differences between arms
Original publication
Summarised from the published abstract; every number is checked against it