Valvular & structural heart diseaseCross-sectional study
Mechanical Wave Velocities in Left Ventricular Walls in Healthy Subjects and Patients With Aortic Stenosis
- Cross-sectional study
Authors' conclusion
MWV estimation during atrial kick is feasible and demonstrates higher velocities in the lateral walls, compared with septal walls.
Study context
- Population
- Healthy subjects and patients with severe aortic stenosis (AS) undergoing high frame rate echocardiographyCMR in 42
- Participants
- 63 vs 13
- Exposure
- Healthy subjects vs patients with severe AS
- Healthyn = 63reference
- Severe ASn = 13
- Outcome
- Mechanical wave velocities (MWVs) in different LV walls at atrial kick and aortic valve closure; feasibility and reproducibility
Main finding
As reported in the abstract
MWV at atrial kick, healthy subjects
Feasibility for atrial kick wave, all 4 examined LV walls
>93%
Mechanical wave velocity (MWV), inferolateral and anterolateral walls
2.2 and 2.6 m/s
MWV, inferoseptal and anteroseptal walls
1.3 and 1.6 m/s
Lateral vs septal walls, higher MWVs
P < 0.05
Observational data: associations, not effects.
Further findings
Septal MWV at aortic valve closure
- Significantly higher in severe AS than in healthy subjects
Original publication
Mechanical Wave Velocities in Left Ventricular Walls in Healthy Subjects and Patients With Aortic Stenosis. JACC Cardiovasc Imaging. Published 6 September 2023. doi:10.1016/j.jcmg.2023.07.009
Summarised from the published abstract; every number is checked against it