Coronary disease & ACSMeta-analysis

Mental health status and quality of life after an acute myocardial infarction with non-obstructive coronary arteries or takotsubo syndrome: a systematic review

Eur J Prev CardiolPublished

  • Systematic review
  • Registered in PROSPERO; reported per PRISMA

Databases searched: Cochrane Library, CINAHL, PyschINFO, PubMed, ASSIA, Web of Science, Scopus and Embase, from inception to May 2024 · Quality and risk of bias assessed with the Newcastle-Ottawa Scale for cross-sectional and cohort studies

Authors' conclusion

Patients with MINOCA or TS seem to have worse mental health status and QoL after the acute event than non-cardiac individuals, but it is yet difficult to conclude whether mental distress and QoL are equal or worse compared to CHD-patients.

Study context

Population
Patients after acute myocardial infarction with non-obstructive coronary arteries (MINOCA) or takotsubo syndrome28 studies
Comparison
MINOCA and takotsubo syndrome (TS) patients vs non-cardiac and cardiac populations, and over time
Outcome
Mental health status and QoL after the acute event

Pooled result

As reported in the abstract

Mental health status or QoL

MINOCA/TS worse than non-cardiac groups

10/13 studies

MINOCA/TS worse than cardiac groups

10/20 studies

Further pooled results

Change over time in mental health status or quality of life (QoL)

Deteriorating mental health status
1/5 studies
Improved mental health status or QoL
3/5 studies
No change
1/5 studies

Risk of bias (Newcastle-Ottawa Scale)

High
18/28
Medium
7/28
Low
3/28

Original publication

Mental health status and quality of life after an acute myocardial infarction with non-obstructive coronary arteries or takotsubo syndrome: a systematic review. Eur J Prev Cardiol. Published 25 February 2025. doi:10.1093/eurjpc/zwaf101

Summarised from the published abstract; every number is checked against it