Coronary disease & ACSCohort study
Minicrush or T-Stenting and Minimal Protrusion in Complex Coronary Bifurcation Lesions: The Multicenter TREX Registry
- multicenter, retrospective cohort study
- consecutive patients
Authors' conclusion
Minicrush and TAP provide comparable long-term efficacy in complex coronary bifurcation percutaneous coronary intervention; however, Minicrush is associated with a lower risk of stent thrombosis, suggesting a more favorable safety profile.
Study context
- Population
- Patients treated with an upfront 2-stent strategy using Minicrush or TAP for complex coronary bifurcation lesions between November 2015 and April 2025underwent an upfront 2-stent strategy, among 601 screened patients · Minicrush 257 · TAP 212
- Participants
- 469 patients
- Exposure
- Minicrush versus TAP stenting techniques
- Minicrushn = 257
- TAPn = 212
- Outcome
- Target lesion failure
- Follow-up
- 1, 5, or 10 years
Main finding
As reported in the abstract
- Target lesion failure occurred in 10.4% of patients, with no significant differences between Minicrush and TAP at 1, 5, or 10 years
- no significant differences between groups at 1, 5, or 10 years
Observational data: associations, not effects.
Secondary outcomes
Major cardiovascular events · all time points
- Major cardiovascular event rates were also comparable across all time points
Predictors (multivariable analyses)
- distal left main involvement and severe coronary calcification were the strongest predictors of TLF
- reduced left ventricular ejection fraction was the main predictor of major cardiovascular events
Safety
Definite or probable stent thrombosis
- Definite or probable stent thrombosis: more frequently with TAP than with Minicrush; P <0.01
Original publication
Minicrush or T-Stenting and Minimal Protrusion in Complex Coronary Bifurcation Lesions: The Multicenter TREX Registry. Circ Cardiovasc Interv. Published 14 September 2026. doi:10.1161/circinterventions.126.016666
Summarised from the published abstract; every number is checked against it