Heart failure & cardiomyopathiesCohort study
Minimally Important Kansas City Cardiomyopathy Questionnaire Changes Across the Spectrum of Heart Failure Severity
- Prospective cohort study
- multicentre
Authors' conclusion
A 5-point difference in KCCQ scores represents an important clinical change for patients, regardless of their baseline health status
Study context
- Population
- Outpatients with HF with EF ≤40% from 14 clinics
- Participants
- 467 outpatients
- Outcome
- MCID for KCCQ-OSS and KCCQ-CSS across the range of baseline health status
- Follow-up
- 6 ± 2 weeks
Main finding
As reported in the abstract
KCCQ-OSS MCID
- Overall KCCQ-OSS minimal clinically important difference (MCID) for improvement or deterioration
- 3.9 (95% CI 2.7-5.4)
- MCID for improvement at baseline Kansas City Cardiomyopathy Questionnaire (KCCQ) of 20
- 6.0 (95% CI 3.8-8.3)
- MCID for improvement at baseline KCCQ of 95
- 2.1 (95% CI −0.0 to 4.5)
- Trend of MCID for improvement across baseline scores
- P-trend = 0.003
- MCIDs for deterioration constant across baseline scores
- P = 0.87
Observational data: associations, not effects.
Further findings
Perceived change in health status (15-point Likert scale) · 6 ± 2 weeks
- Moderate/large deteriorations
- 28
- Small but important deteriorations
- 28
- No change
- 293
- Small but important improvements
- 35
- Moderate/large improvements
- 83
Original publication
Minimally Important Kansas City Cardiomyopathy Questionnaire Changes Across the Spectrum of Heart Failure Severity. JACC Heart Fail. doi:10.1016/j.jchf.2025.102587
Summarised from the published abstract; every number is checked against it