Heart failure & cardiomyopathiesResearch article
Mitral Interventions in Heart Failure
- Narrative review
Authors' conclusion
A spectrum of transcatheter devices in development and clinical trials promise to further provide a growing array of management options for heart failure with reduced ejection fraction patients with symptomatic SMR.
Study context
- Population
- HFrEF patients with secondary mitral regurgitation (SMR)
Main finding
As reported in the abstract
Role of mitral transcatheter edge-to-edge repair in HFrEF with secondary mitral regurgitation (narrative review)
- HFrEF patients with SMR have poorer outcomes and quality of life than those without SMR
- Guideline-directed medical therapy is the cornerstone of SMR treatment
- Landmark mitral TEER trials in SMR improved understanding of who benefits from percutaneous intervention, with emphasis on a multidisciplinary approach
- TEER success in SMR has spurred evaluation in populations not initially studied, e.g. end-stage HF and cardiogenic shock
Original publication
Mitral Interventions in Heart Failure. JACC Heart Fail. doi:10.1016/j.jchf.2023.07.016
Summarised from the published abstract; every number is checked against it