Valvular & structural heart diseaseResearch article

Mitral Valve Leaflet Modification

JACC Cardiovasc IntervPublished

  • State-of-the-art review

Study context

Population
Patients undergoing transcatheter mitral valve replacement (TMVR) at risk of left ventricular outflow tract (LVOT) obstruction

Main finding

As reported in the abstract

Prevention of TMVR-induced LVOT obstruction by mitral leaflet modification
  • Intentional LAMPOON and related techniques effectively prevent TMVR-induced LVOT obstruction, expanding the treatable population
  • Risk of LVOT obstruction can reliably be identified on preprocedural cardiac CT

Original publication

Mitral Valve Leaflet Modification. JACC Cardiovasc Interv. Published 22 June 2026. doi:10.1016/j.jcin.2026.04.029

Summarised from the published abstract; every number is checked against it