Heart failure & cardiomyopathiesCohort study
Mortality in heart failure with and without autoimmune disease
- Retrospective cohort study
- nationwide
- matched cohort
Authors' conclusion
In a nationwide cohort study, patients with HF and a history of AID had a higher associated rate of mortality than those without a history of AID.
Study context
- Population
- Patients with heart failure (HF) diagnosed 2000–18, Danish nationwide registriesmatched cohort
- Exposure
- HF with history of AID vs HF without AID
- Outcome
- All-cause mortality and HF hospitalization
- Follow-up
- Median 3.2 years
Main finding
As reported in the abstract
AID
17.1 (95% CI 16.9-17.4)
All-cause mortality per 100 person-years · HF hospitalization per 100 person-years 5.0 (4.9-5.1)
No AID
14.4 (14.3-14.6)
All-cause mortality per 100 person-years · HF hospitalization per 100 person-years 5.2 (5.1-5.4)
AID vs No AIDHazard ratio (CI)
all-cause mortality
1.14(1.12–1.17)
HF hospitalization
1.00(0.96–1.04)
Observational data: associations, not effects.
Further findings
Prevalence of AID in patients with HF
- Prevalence of AID in HF
- 10.7%
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Mortality in heart failure with and without autoimmune disease. Eur J Prev Cardiol. Published 23 February 2023. doi:10.1093/eurjpc/zwad056
Summarised from the published abstract; every number is checked against it