Myocardial Blood Flow by Magnetic Resonance in Patients With Suspected Coronary Stenosis: Comparison to PET and Invasive Physiology
Authors' conclusion
CMR-QP correlates weakly to myocardial blood flow measurements by other modalities but improves diagnosis of anatomically severe CAD.
Study context
- Population
- Symptomatic patients with >50% diameter stenosis on CT angiographyAbout 359 completed all investigations
- Comparison
- CMR-QP vs PET vs invasive thermodilution (ICA-CFR) for myocardial blood flow; CMR-QP added to visual expert read vs visual read alone
- Outcome
- Correlation between myocardial blood flow measurements by CMR, PET and invasive coronary thermodilution
Performance
As reported in the abstract
Correlation of myocardial blood flow and reserve between CMR-QP, PET and ICA-CFR
Correlated weakly for all comparisons
r<0.40
Further findings
Diagnosis of anatomically severe coronary artery disease (CAD) (>70% diameter stenosis on QCA): expert read with CMR-QP vs visual analysis alone
- Sensitivity improved with CMR-QP (82% versus 88%, as printed)
- P = 0.03
- Specificity not compromised (77% versus 74%, as printed)
- P = 0.28
Diagnosis of hemodynamically obstructive CAD (FFR ≤0.80)
- Accuracy only moderate for visual expert read; unchanged with additional CMR-QP
Original publication
Myocardial Blood Flow by Magnetic Resonance in Patients With Suspected Coronary Stenosis: Comparison to PET and Invasive Physiology. Circ Cardiovasc Imaging. Published 18 June 2024. doi:10.
Summarised from the published abstract; every number is checked against it