Aortic & peripheral vascular diseaseCohort study
Nationwide analysis of the relationship between low ambient temperature and acute aortic dissection-related hospitalizations
- Time-stratified case-crossover study
- nationwide
- claims-based database
- conditional logistic regression
- distributed lag non-linear models
Authors' conclusion
Low AT is associated with an increased risk of AAD-related hospitalization.
Study context
- Population
- Patients hospitalized with acute aortic dissection at 1119 certified Japanese hospitals (JROAD-DPC), 2012–2020cases analysed
- Participants
- 96,812 patients
- Exposure
- Low vs moderate ambient temperature
- Outcome
- AAD-related hospitalization by average daily ambient temperature
Main finding
AAD-related hospitalization
Odds ratio
2.28
95% CI 1.92–2.71
−10°C vs 20°C
OR 2.28 (95% CI 1.92–2.71)
As reported in the abstract
Observational data: associations, not effects.
Further findings
Acute aortic dissection (AAD)-related hospitalization by subgroup (stratified analyses)
- Greater association with older age (≥75 years), female sex, low BMI (<22), winter season and warmer regions
Original publication
Nationwide analysis of the relationship between low ambient temperature and acute aortic dissection-related hospitalizations. Eur J Prev Cardiol. Published 21 August 2024. doi:10.1093/eurjpc/zwae278
Summarised from the published abstract; every number is checked against it