Cardiometabolic & kidney

Nationwide cardiovascular risk categorization: applying the European Society of Cardiology guidelines to the Swedish National Diabetes Register

Eur J Prev CardiolPublished Registry-based cohort study

Authors' conclusion

This analysis highlights differences between previous prescribing practices in Sweden and the 2021 ESC guidelines

Study context

Population
Patients with T2DM aged 18–90 years in the Swedish National Diabetes Register not receiving cardiovascular (CV)-protective glucose-lowering medication in 2017129,512 at very high cardiovascular disease (CVD) risk
Participants
320,028 patients
Outcome
MACE:
  • CV death
  • Non-fatal stroke
  • Non-fatal MI
Follow-up
2017
Methodological detailsnationwide
  • Nationwide

Main finding

As reported in the abstract

MACE incidence

Very high CVD risk (European Society of Cardiology (ESC) criteria)

75.4 events/1000 person-years

Atherosclerotic CVD (ASCVD) with elevated HbA1c (>9%)

136.5 events/1000 person-years

ASCVD without elevated HbA1c

90.8 events/1000 person-years

Observational data: associations, not effects.

Further findings

Estimated MACE avoided with semaglutide (very high CVD risk and ASCVD) · 2017

MACE that may have been avoided
803
  • Estimated

Original publication

Nationwide cardiovascular risk categorization: applying the European Society of Cardiology guidelines to the Swedish National Diabetes Register. Eur J Prev Cardiol. Published 26 December 2022. doi:10.1093/eurjpc/zwac308

Composed by AI from the published abstract and checked against it. How Briefs are made →

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