Heart failure & cardiomyopathiesCohort study
Nationwide Implementation of Heart Failure Therapies: National Heart Failure Center Accreditation Program (HF-CAP) in China
- Prospective longitudinal pre-post comparison study
- nationwide
- multicentre
Authors' conclusion
Guideline-directed medical therapy implementation and follow-up after HF hospitalization was achievable in ~400 000 patients and was associated with cardiovascular benefits 1-year post-initiation.
Study context
- Population
- Patients with heart failure (HF) in hospitals accredited by the National Heart Failure Center Accreditation Program (HF-CAP), China
- Participants
- 408,073 patients · 646 centres
- Exposure
- After vs before HF-CAP accreditation
- Outcome
- Composite:
- HF readmission
- CV death
- Follow-up
- 1 year
Main finding
As reported in the abstract
HF readmission and/or CV death
Each group vs preOdds ratio (95% CI)P value
Y1
0.893(0.871–0.916)
P < 0.0001Y2
0.855(0.830–0.880)
P < 0.0001Y2+
0.720(0.695–0.745)
P < 0.0001Observational data: associations, not effects.
Secondary outcomes
| Outcome | OR (95% CI) | |
|---|---|---|
| HF readmission alone · 1 year · reduced from Y1 onwards | 0.865 (0.841–0.891) | |
| CV death alone · 1 year · reduced from Y2 onwards | 0.942 (0.904–0.983) | |
| Follow-up contact and outcomes · CV death | 0.624 (0.597–0.651) | |
| 0.512Odds ratio (log scale) |
Follow-up contact and outcomes
- Phone calls had little association with patient outcomes
Original publication
Nationwide Implementation of Heart Failure Therapies: National Heart Failure Center Accreditation Program (HF-CAP) in China. Eur J Heart Fail. Published 22 September 2025. doi:10.1002/ejhf.70035
Summarised from the published abstract; every number is checked against it