Congenital heart diseaseResearch article

Natural Shear Wave Elastography

JACC AdvPublished

  • Fontan patients compared with age-matched healthy volunteers

Authors' conclusion

Our findings suggest that Fontan hearts may be stiffer than normal and that SW velocities are higher in patients with a Fontan circulatory failure. Moreover, SW speed was related to SVP.

Study context

Population
Fontan patientsFontan patients, SVP available in n = 30
Participants
47 patients
Comparison
Shear wave (SW) speed in Fontan patients vs age-matched healthy volunteers
  • Fontan patientsn = 47

Main finding

As reported in the abstract

Average SW speed after AVVC

P < 0.001

Further findings

Average SW speed after outflow valve closure · higher in Fontan patients

P < 0.001

OutcomeP value
SW speed, Fontan circulatory failure vs well-functioning Fontan patients · increased with Fontan circulatory failureP = 0.008
  • SW speed, Fontan circulatory failure vs well-functioning Fontan patients: Fontan circulatory failure 6.3 ± 1.4 m/s
  • SW speed, Fontan circulatory failure vs well-functioning Fontan patients: well-functioning Fontan patients 4.9 ± 1.5 m/s

Correlation of SW velocities after atrioventricular valve closure (AVVC) with SVP

r
0.55
P
P = 0.002
no other conventional diastolic parameter correlated to SVP

Original publication

Natural Shear Wave Elastography. JACC Adv. Published 20 February 2026. doi:10.1016/j.jacadv.2026.102608

Summarised from the published abstract; every number is checked against it