Acute cardiac care & resuscitation
Neurological outcome of out-of-hospital cardiac arrest patients ventilated with continuous flow insufflation of oxygen: a multicenter observational study
Main finding · Favorable neurological status according to the Cerebral Performance Category (CPC) scale (CPC 1 or 2)Result — go to the resultAdjusted odds ratio 0.61 95% CI 0.41–0.9Authors' conclusion
The use of CFIO during OHCA was associated with significantly lower odds of favorable neurological outcome at day 30 compared to BVM.
Study context
- Population
- Adult patients from the Northern French Alps Emergency Network cardiac arrest registry who experienced out-of-hospital cardiac arrest (OHCA) in three different Emergency Medical Systems between 2017 and 2021
- Participants
- 2,237 included patients
- Exposure
- Continuous flow insufflation of oxygen (CFIO) versus bag-valve-mask ventilation
- CFIOn = 967
- Bag-valve-mask (BVM)n = 1,270reference
- Outcome
- Favorable neurological status according to the Cerebral Performance Category (CPC) scale (CPC 1 or 2)
- Follow-up
- 30 days
Main finding
As reported in the abstract
Favorable neurological status according to the Cerebral Performance Category (CPC) scale (CPC 1 or 2)
Adjusted odds ratio
0.61
95% CI 0.41–0.9
P = 0.01
CFIO vs BVM
adjusted OR 0.61 (95% CI 0.41–0.9); P = 0.01
Observational data: associations, not effects.
Original publication
Neurological outcome of out-of-hospital cardiac arrest patients ventilated with continuous flow insufflation of oxygen: a multicenter observational study. Resuscitation. Published 30 April 2026. doi:10.
Summarised from the published abstract; every number is checked against it