Coronary disease & ACS

New Angiographic Difficulty Score for First-Attempt Chronic Total Occlusion in the 3 Major Coronary Arteries

JACC Cardiovasc IntervPublished Registry-based cohort study

Authors' conclusion

Clinical and angiographic differences might explain the discrepancies of success rates in CTO lesions among the 3 major coronary arteries. Our novel difficulty score was comparable to the J-CTO score in predicting unsuccessful CTO-PCI with a superior discriminatory capacity.

Study context

Population
First-attempt chronic total occlusion (CTO) percutaneous coronary intervention (PCI) patients, Japanese CTO-PCI expert registry, January 2014 to December 2021
Participants
6,408 patients
Exposure
Artery-specific difficulty scores vs J-CTO score for predicting unsuccessful CTO-PCI
  • Left anterior descending coronary arteryn = 2,245
  • Left circumflex coronary arteryn = 1,131
  • Right coronary artery (RCA)n = 3,032
Outcome
Predictors of unsuccessful PCI in first-attempt CTO lesions of the 3 major coronary arteries, compared with the J-CTO score
Methodological detailsdifficulty score derivation and validation, multicentre registry, derivation and validation sets
  • Difficulty score derivation and validation
  • Multicentre registry
  • Derivation and validation sets

Main finding

As reported in the abstract

Procedural success rate

Observational data: associations, not effects.

Further findings

RCA CTO lesion characteristics

RCA CTO significantly longer and more severely angulated, more often requiring the retrograde approach

Original publication

New Angiographic Difficulty Score for First-Attempt Chronic Total Occlusion in the 3 Major Coronary Arteries. JACC Cardiovasc Interv. Published 23 October 2023. doi:10.1016/j.jcin.2023.08.046

Summarised from the published abstract; every number is checked against it

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